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Publikationen

2025

Crystal structure of the class V GTP-binding RNA aptamer bound to its ligand: GTP recognition by a topologically complex intermolecular G-quadruplex. 

Stafflinger H, Neißner K, Bartsch S, Pichler AK, Bartosik K, Dhamotharan K, Abele R, Duchardt-Ferner E, Micura R, Schindelin H, Wöhnert J.

Nucleic Acids Res. 2025 Nov 26;53(22):gkaf1315. doi: 10.1093/nar/gkaf1315. PMID: 41422825 

 

Structural basis for ligand recognition in the tobramycin riboswitch. 

Duchardt-Ferner E, Kraus L, Limouchi A, Suess B, Wöhnert J.

Nucleic Acids Res. 2025 Aug 27;53(16):gkaf817. doi: 10.1093/nar/gkaf817. PMID: 40902004

 

Protonated Glutamate and Aspartate Side Chains Can Recognize Phosphodiester Groups via Strong and Short Hydrogen Bonds in Biomacromolecular Complexes. 

Neißner K, Duchardt-Ferner E, Wiedemann C, Kraus J, Hellmich UA, Wöhnert J.

Angew Chem Int Ed Engl. 2025 Jul;64(27):e202501589. doi: 10.1002/anie.202501589. Epub 2025 May 30. PMID: 40272996

 

Investigating the Conformational Diversity of the TMR-3 Aptamer. 

Gauger M, Duchardt-Ferner E, Halbritter AJ, Hetzke T, Sigurdsson ST, Wöhnert J, Prisner TF.

J Am Chem Soc. 2025 May 21;147(20):17497-17509. doi: 10.1021/jacs.5c04576. Epub 2025 May 12. PMID: 40356230

 

NMR Solution Structure of the N-Terminal GSPII Domain from the Thermus Thermophilus Traffic ATPase PilF and Reconstruction of its c-di-GMP Binding Capability. 

Neißner K, Frohnapfel C, Keller H, Duchardt-Ferner E, Schneider V, Kamjou Z, Averhoff B, Wöhnert

J. Chembiochem. 2025 Apr 1;26(7):e202400959. doi: 10.1002/cbic.202400959. Epub 2025 Mar 12. PMID: 39960869

 

Chemical reactivity of RNA and its modifications with hydrazine. 

Yeşiltaç-Tosun N, Qi Y, Li C, Stafflinger H, Hollnagel K, Rusling L, Wöhnert J, Kaiser S, Kaiser S.

Commun Chem. 2025 Feb 14;8(1):48. doi: 10.1038/s42004-025-01444-y. PMID: 39953096

 

The structural basis for high-affinity c-di-GMP binding to the GSPII-B domain of the traffic ATPase PilF from Thermus thermophilus. 

Neißner K, Keller H, Kirchner L, Düsterhus S, Duchardt-Ferner E, Averhoff B, Wöhnert J.

J Biol Chem. 2025 Jan;301(1):108041. doi: 10.1016/j.jbc.2024.108041. Epub 2024 Nov 29. PMID: 39615687

2023

Development of a novel tobramycin dependent riboswitch. 

Kraus L, Duchardt-Ferner E, Bräuchle E, Fürbacher S, Kelvin D, Marx H, Boussebayle A, Maurer LM, Bofill-Bosch C, Wöhnert J, Suess B.

Nucleic Acids Res. 2023 Nov 10;51(20):11375-11385. doi: 10.1093/nar/gkad767. PMID: 37791877

 

High-resolution structure of stem-loop 4 from the 5'-UTR of SARS-CoV-2 solved by solution state NMR. 

Vögele J, Hymon D, Martins J, Ferner J, Jonker HRA, Hargrove AE, Weigand JE, Wacker A, Schwalbe H, Wöhnert J, Duchardt-Ferner E.

Nucleic Acids Res. 2023 Nov 10;51(20):11318-11331. doi: 10.1093/nar/gkad762. PMID: 37791874

 

Multi-Site Conformational Exchange in the Synthetic Neomycin-Sensing Riboswitch Studied by 19 F NMR. 

Overbeck JH, Vögele J, Nussbaumer F, Duchardt-Ferner E, Kreutz C, Wöhnert J, Sprangers R.

Angew Chem Int Ed Engl. 2023 Jun 5;62(23):e202218064. doi: 10.1002/anie.202218064. Epub 2023 Apr 28. PMID: 36970768 

 

Structural and dynamic effects of pseudouridine modifications on noncanonical interactions in RNA. 

Vögele J, Duchardt-Ferner E, Kruse H, Zhang Z, Sponer J, Krepl M, Wöhnert J.

RNA. 2023 Jun;29(6):790-807. doi: 10.1261/rna.079506.122. Epub 2023 Mar 3. PMID: 36868785 

2022

Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development. 

Berg H, Wirtz Martin MA, Altincekic N, Alshamleh I, Kaur Bains J, Blechar J, Ceylan B, de Jesus V, Dhamotharan K, Fuks C, Gande SL, Hargittay B, Hohmann KF, Hutchison MT, Marianne Korn S, Krishnathas R, Kutz F, Linhard V, Matzel T, Meiser N, Niesteruk A, Pyper DJ, Schulte L, Trucks S, Azzaoui K, Blommers MJJ, Gadiya Y, Karki R, Zaliani A, Gribbon P, da Silva Almeida M, Dinis Anobom C, Bula AL, Bütikofer M, Putinhon Caruso Í, Caterina Felli I, Da Poian AT, Cardoso de Amorim G, Fourkiotis NK, Gallo A, Ghosh D, Gomes-Neto F, Gorbatyuk O, Hao B, Kurauskas V, Lecoq L, Li Y, Cunha Mebus-Antunes N, Mompeán M, Cristtina Neves-Martins T, Ninot-Pedrosa M, Pinheiro AS, Pontoriero L, Pustovalova Y, Riek R, Robertson AJ, Jose Abi Saad M, Treviño MÁ, Tsika AC, Almeida FCL, Bax A, Henzler-Wildman K, Hoch JC, Jaudzems K, Laurents DV, Orts J, Pierattelli R, Spyroulias GA, Duchardt-Ferner E, Ferner J, Fürtig B, Hengesbach M, Löhr F, Qureshi N, Richter C, Saxena K, Schlundt A, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J, Schwalbe H.

Angew Chem Int Ed Engl. 2022 Sep 17:e202205858. doi: 10.1002/anie.202205858. Online ahead of print. PMID: 36115062 

 

NMR assignment of non-modified tRNAIle from Escherichia coli. 

de Jesus V, Biedenbänder T, Vögele J, Wöhnert J, Fürtig B.

Biomol NMR Assign. 2022 Apr;16(1):165-170. doi: 10.1007/s12104-022-10075-6. Epub 2022 Mar 11. PMID: 35275364 

 

1H, 13C and 15N chemical shift assignment of the stem-loops 5b + c from the 5'-UTR of SARS-CoV-2. 

Mertinkus KR, Grün JT, Altincekic N, Bains JK, Ceylan B, Ferner JP, Frydman L, Fürtig B, Hengesbach M, Hohmann KF, Hymon D, Kim J, Knezic B, Novakovic M, Oxenfarth A, Peter SA, Qureshi NS, Richter C, Scherf T, Schlundt A, Schnieders R, Schwalbe H, Stirnal E, Sudakov A, Vögele J, Wacker A, Weigand JE, Wirmer-Bartoschek J, Martin MAW, Wöhnert J.

Biomol NMR Assign. 2022 Apr;16(1):17-25. doi: 10.1007/s12104-021-10053-4. Epub 2022 Feb 18. PMID: 35178672 

2021

1H, 13C and 15N assignment of stem-loop SL1 from the 5'-UTR of SARS-CoV-2. 

Richter C, Hohmann KF, Toews S, Mathieu D, Altincekic N, Bains JK, Binas O, Ceylan B, Duchardt-Ferner E, Ferner J, Fürtig B, Grün JT, Hengesbach M, Hymon D, Jonker HRA, Knezic B, Korn SM, Landgraf T, Löhr F, Peter SA, Pyper DJ, Qureshi NS, Schlundt A, Schnieders R, Stirnal E, Sudakov A, Vögele J, Weigand JE, Wirmer-Bartoschek J, Witt K, Wöhnert J, Schwalbe H, Wacker A.

Biomol NMR Assign. 2021 Oct;15(2):467-474. doi: 10.1007/s12104-021-10047-2. Epub 2021 Aug 28. PMID: 34453696 

 

1H, 13C, 15N and 31P chemical shift assignment for stem-loop 4 from the 5'-UTR of SARS-CoV-2. 

Vögele J, Ferner JP, Altincekic N, Bains JK, Ceylan B, Fürtig B, Grün JT, Hengesbach M, Hohmann KF, Hymon D, Knezic B, Löhr F, Peter SA, Pyper D, Qureshi NS, Richter C, Schlundt A, Schwalbe H, Stirnal E, Sudakov A, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J, Duchardt-Ferner E.

Biomol NMR Assign. 2021 Oct;15(2):335-340. doi: 10.1007/s12104-021-10026-7. Epub 2021 Apr 29. PMID: 33928512 

 

Exploring the Druggability of Conserved RNA Regulatory Elements in the SARS-CoV-2 Genome. 

Sreeramulu S, Richter C, Berg H, Wirtz Martin MA, Ceylan B, Matzel T, Adam J, Altincekic N, Azzaoui K, Bains JK, Blommers MJJ, Ferner J, Fürtig B, Göbel M, Grün JT, Hengesbach M, Hohmann KF, Hymon D, Knezic B, Martins JN, Mertinkus KR, Niesteruk A, Peter SA, Pyper DJ, Qureshi NS, Scheffer U, Schlundt A, Schnieders R, Stirnal E, Sudakov A, Tröster A, Vögele J, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J, Schwalbe H.

Angew Chem Int Ed Engl. 2021 Aug 23;60(35):19191-19200. doi: 10.1002/anie.202103693. Epub 2021 Aug 3. PMID: 34161644 

 

Correction to 'Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy'. 

Wacker A, Weigand JE, Akabayov SR, Altincekic N, Bains JK, Banijamali E, Binas O, Castillo-Martinez J, Cetiner E, Ceylan B, Chiu LY, Davila-Calderon J, Dhamotharan K, Duchardt-Ferner E, Ferner J, Frydman L, Fürtig B, Gallego J, Grün JT, Hacker C, Haddad C, Hähnke M, Hengesbach M, Hiller F, Hohmann KF, Hymon D, de Jesus V, Jonker H, Keller H, Knezic B, Landgraf T, Löhr F, Luo L, Mertinkus KR, Muhs C, Novakovic M, Oxenfarth A, Palomino-Schätzlein M, Petzold K, Peter SA, Pyper DJ, Qureshi NS, Riad M, Richter C, Saxena K, Schamber T, Scherf T, Schlagnitweit J, Schlundt A, Schnieders R, Schwalbe H, Simba-Lahuasi A, Sreeramulu S, Stirnal E, Sudakov A, Tants JN, Tolbert BS, Vögele J, Weiß L, Wirmer-Bartoschek J, Wirtz Martin MA, Wöhnert J, Zetzsche H.

Nucleic Acids Res. 2021 Jul 9;49(12):7204-7205. doi: 10.1093/nar/gkab568. PMID: 34161581 

 

Cooperation between a T Domain and a Minimal C-Terminal Docking Domain to Enable Specific Assembly in a Multiprotein NRPS. 

Watzel J, Duchardt-Ferner E, Sarawi S, Bode HB, Wöhnert J.

Angew Chem Int Ed Engl. 2021 Jun 14;60(25):14171-14178. doi: 10.1002/anie.202103498. Epub 2021 May 14. PMID: 33876501 

 

NMR resonance assignments for a docking domain pair with an attached thiolation domain from the PAX peptide-producing NRPS from Xenorhabdus cabanillasii. 

Watzel J, Sarawi S, Duchardt-Ferner E, Bode HB, Wöhnert J.

Biomol NMR Assign. 2021 Apr;15(1):229-234. doi: 10.1007/s12104-021-10010-1. Epub 2021 Mar 5. PMID: 33675014 

 

1H, 13C and 15N chemical shift assignment of the stem-loop 5a from the 5'-UTR of SARS-CoV-2. 

Schnieders R, Peter SA, Banijamali E, Riad M, Altincekic N, Bains JK, Ceylan B, Fürtig B, Grün JT, Hengesbach M, Hohmann KF, Hymon D, Knezic B, Oxenfarth A, Petzold K, Qureshi NS, Richter C, Schlagnitweit J, Schlundt A, Schwalbe H, Stirnal E, Sudakov A, Vögele J, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J.

Biomol NMR Assign. 2021 Apr;15(1):203-211. doi: 10.1007/s12104-021-10007-w. Epub 2021 Jan 23. PMID: 33484403 

 

1H, 13C, and 15N backbone chemical shift assignments of the C-terminal dimerization domain of SARS-CoV-2 nucleocapsid protein. 

Korn SM, Lambertz R, Fürtig B, Hengesbach M, Löhr F, Richter C, Schwalbe H, Weigand JE, Wöhnert J, Schlundt A.

Biomol NMR Assign. 2021 Apr;15(1):129-135. doi: 10.1007/s12104-020-09995-y. Epub 2020 Dec 3. PMID: 33270159 

 

1H, 13C, and 15N backbone chemical shift assignments of coronavirus-2 non-structural protein Nsp10. 

Kubatova N, Qureshi NS, Altincekic N, Abele R, Bains JK, Ceylan B, Ferner J, Fuks C, Hargittay B, Hutchison MT, de Jesus V, Kutz F, Wirtz Martin MA, Meiser N, Linhard V, Pyper DJ, Trucks S, Fürtig B, Hengesbach M, Löhr F, Richter C, Saxena K, Schlundt A, Schwalbe H, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Wöhnert J.

Biomol NMR Assign. 2021 Apr;15(1):65-71. doi: 10.1007/s12104-020-09984-1. Epub 2020 Nov 7. PMID: 33159807 

 

Phosphorothioate Substitutions in RNA Structure Studied by Molecular Dynamics Simulations, QM/MM Calculations, and NMR Experiments. 

Zhang Z, Vögele J, Mráziková K, Kruse H, Cang X, Wöhnert J, Krepl M, Šponer J.

J Phys Chem B. 2021 Jan 28;125(3):825-840. doi: 10.1021/acs.jpcb.0c10192. Epub 2021 Jan 20. PMID: 33467852 

2020

Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy. 

Wacker A, Weigand JE, Akabayov SR, Altincekic N, Bains JK, Banijamali E, Binas O, Castillo-Martinez J, Cetiner E, Ceylan B, Chiu LY, Davila-Calderon J, Dhamotharan K, Duchardt-Ferner E, Ferner J, Frydman L, Fürtig B, Gallego J, Grün JT, Hacker C, Haddad C, Hähnke M, Hengesbach M, Hiller F, Hohmann KF, Hymon D, de Jesus V, Jonker H, Keller H, Knezic B, Landgraf T, Löhr F, Luo L, Mertinkus KR, Muhs C, Novakovic M, Oxenfarth A, Palomino-Schätzlein M, Petzold K, Peter SA, Pyper DJ, Qureshi NS, Riad M, Richter C, Saxena K, Schamber T, Scherf T, Schlagnitweit J, Schlundt A, Schnieders R, Schwalbe H, Simba-Lahuasi A, Sreeramulu S, Stirnal E, Sudakov A, Tants JN, Tolbert BS, Vögele J, Weiß L, Wirmer-Bartoschek J, Wirtz Martin MA, Wöhnert J, Zetzsche H.

Nucleic Acids Res. 2020 Dec 16;48(22):12415-12435. doi: 10.1093/nar/gkaa1013. PMID: 33167030 

 

Solution structure and RNA-binding of a minimal ProQ-homolog from Legionella pneumophila (Lpp1663). 

Immer C, Hacker C, Wöhnert J.

RNA. 2020 Dec;26(12):2031-2043. doi: 10.1261/rna.077354.120. Epub 2020 Sep 28. PMID: 32989045 

 

LILBID laser dissociation curves: a mass spectrometry-based method for the quantitative assessment of dsDNA binding affinities. 

Young P, Hense G, Immer C, Wöhnert J, Morgner N.

Sci Rep. 2020 Nov 23;10(1):20398. doi: 10.1038/s41598-020-76867-9. PMID: 33230224 

 

1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b. 

Cantini F, Banci L, Altincekic N, Bains JK, Dhamotharan K, Fuks C, Fürtig B, Gande SL, Hargittay B, Hengesbach M, Hutchison MT, Korn SM, Kubatova N, Kutz F, Linhard V, Löhr F, Meiser N, Pyper DJ, Qureshi NS, Richter C, Saxena K, Schlundt A, Schwalbe H, Sreeramulu S, Tants JN, Wacker A, Weigand JE, Wöhnert J, Tsika AC, Fourkiotis NK, Spyroulias GA.

Biomol NMR Assign. 2020 Oct;14(2):339-346. doi: 10.1007/s12104-020-09973-4. Epub 2020 Aug 14. PMID: 32803496 

 

1H, 13C, and 15N backbone chemical shift assignments of the nucleic acid-binding domain of SARS-CoV-2 non-structural protein 3e. 

Korn SM, Dhamotharan K, Fürtig B, Hengesbach M, Löhr F, Qureshi NS, Richter C, Saxena K, Schwalbe H, Tants JN, Weigand JE, Wöhnert J, Schlundt A.

Biomol NMR Assign. 2020 Oct;14(2):329-333. doi: 10.1007/s12104-020-09971-6. Epub 2020 Aug 8. PMID: 32770392 

 

A New Docking Domain Type in the Peptide-Antimicrobial-Xenorhabdus Peptide Producing Nonribosomal Peptide Synthetase from Xenorhabdus bovienii. 

Watzel J, Hacker C, Duchardt-Ferner E, Bode HB, Wöhnert J.

ACS Chem Biol. 2020 Apr 17;15(4):982-989. doi: 10.1021/acschembio.9b01022. Epub 2020 Mar 25. PMID: 32167274 

 

Identification of the 3-amino-3-carboxypropyl (acp) transferase enzyme responsible for acp3U formation at position 47 in Escherichia coli tRNAs. 

Meyer B, Immer C, Kaiser S, Sharma S, Yang J, Watzinger P, Weiß L, Kotter A, Helm M, Seitz HM, Kötter P, Kellner S, Entian KD, Wöhnert J.

Nucleic Acids Res. 2020 Feb 20;48(3):1435-1450. doi: 10.1093/nar/gkz1191. PMID: 31863583 

 

Crystal structure of the translation recovery factor Trf from Sulfolobus solfataricus.

Kaiser M, Wurm JP, Märtens B, Bläsi U, Pogoryelov D, Wöhnert J.

FEBS Open Bio. 2020 Feb;10(2):221-228. doi: 10.1002/2211-5463.12772. Epub 2019 Dec 18. PMID: 31804766 

 

Structure of an RNA aptamer in complex with the fluorophore tetramethylrhodamine. 

Duchardt-Ferner E, Juen M, Bourgeois B, Madl T, Kreutz C, Ohlenschläger O, Wöhnert J.

Nucleic Acids Res. 2020 Jan 24;48(2):949-961. doi: 10.1093/nar/gkz1113. PMID: 31754719 

 

Gemeinschaftlich in Krisenzeiten: NMR-Strukturbiologie gegen COVID-19. 

Schlundt A, Wirtz MA, Knezic B, Hengesbach M, Fürtig B, Weigand JE, Wöhnert J, Ferner J, Saxena K, Wacker A, Richter C, Sreeramulu S, Wirmer-Bartoschek J, Schwalbe H; Im Namen von Mehr als 50 Wissenschaftlerinnen und Wissenschaftlern in Frankfurt und Darmstadt.

Biospektrum (Heidelb). 2020;26(4):440-441. doi: 10.1007/s12268-020-1396-0. Epub 2020 Jun 26. PMID: 32834541 

2019

NMR resonance assignments for the GSPII-B domain of the traffic ATPase PilF from Thermus thermophilus in the apo and the c-di-GMP-bound state. 

Neißner K, Keller H, Duchardt-Ferner E, Hacker C, Kruse K, Averhoff B, Wöhnert J.

Biomol NMR Assign. 2019 Oct;13(2):383-390. doi: 10.1007/s12104-019-09911-z. Epub 2019 Aug 20. PMID: 31432400 

 

NMR resonance assignments for the GSPII-C domain of the PilF ATPase from Thermus thermophilus in complex with c-di-GMP. 

Keller H, Kruse K, Averhoff B, Duchardt-Ferner E, Wöhnert J.

Biomol NMR Assign. 2019 Oct;13(2):361-366. doi: 10.1007/s12104-019-09906-w. Epub 2019 Aug 1. PMID: 31372934 

 

1H, 13C, 15N backbone NMR resonance assignments for the rRNA methyltransferase Dim1 from the hyperthermophilic archaeon Pyrococcus horikoshii. 

Kaiser M, Hacker C, Duchardt-Ferner E, Wöhnert J.

Biomol NMR Assign. 2019 Oct;13(2):309-314. doi: 10.1007/s12104-019-09897-8. Epub 2019 May 8. PMID: 31069720 

 

NMR resonance assignments for the GTP-binding RNA aptamer 9-12 in complex with GTP. 

Wolter AC, Pianu A, Kremser J, Strebitzer E, Schnieders R, Fürtig B, Kreutz C, Duchardt-Ferner E, Wöhnert J.

Biomol NMR Assign. 2019 Oct;13(2):281-286. doi: 10.1007/s12104-019-09892-z. Epub 2019 Apr 27. PMID: 31030336 

 

Novel 13 C-detected NMR Experiments for the Precise Detection of RNA Structure. 

Schnieders R, Wolter AC, Richter C, Wöhnert J, Schwalbe H, Fürtig B.

Angew Chem Int Ed Engl. 2019 Jul 1;58(27):9140-9144. doi: 10.1002/anie.201904057. Epub 2019 May 27. PMID: 31131949 

 

The structure of the SAM/SAH-binding riboswitch. 

Weickhmann AK, Keller H, Wurm JP, Strebitzer E, Juen MA, Kremser J, Weinberg Z, Kreutz C, Duchardt-Ferner E, Wöhnert J.

Nucleic Acids Res. 2019 Mar 18;47(5):2654-2665. doi: 10.1093/nar/gky1283. PMID: 30590743 

2018

Structure-based redesign of docking domain interactions modulates the product spectrum of a rhabdopeptide-synthesizing NRPS. 

Hacker C, Cai X, Kegler C, Zhao L, Weickhmann AK, Wurm JP, Bode HB, Wöhnert J.

Nat Commun. 2018 Oct 19;9(1):4366. doi: 10.1038/s41467-018-06712-1. PMID: 30341296 

 

NMR resonance assignments for the SAM/SAH-binding riboswitch RNA bound to S-adenosylhomocysteine. 

Weickhmann AK, Keller H, Duchardt-Ferner E, Strebitzer E, Juen MA, Kremser J, Wurm JP, Kreutz C, Wöhnert J.

Biomol NMR Assign. 2018 Oct;12(2):329-334. doi: 10.1007/s12104-018-9834-3. Epub 2018 Jul 26. PMID: 30051308 

 

Adenine protonation enables cyclic-di-GMP binding to cyclic-GAMP sensing riboswitches. 

Keller H, Weickhmann AK, Bock T, Wöhnert J.

RNA. 2018 Oct;24(10):1390-1402. doi: 10.1261/rna.067470.118. Epub 2018 Jul 13. PMID: 30006500 

 

NMR resonance assignments for a ProQ homolog from Legionella pneumophila. 

Immer C, Hacker C, Wöhnert J.

Biomol NMR Assign. 2018 Oct;12(2):319-322. doi: 10.1007/s12104-018-9831-6. Epub 2018 Jun 22. PMID: 29934867 

 

Small but large enough: structural properties of armless mitochondrial tRNAs from the nematode Romanomermis culicivorax. 

Jühling T, Duchardt-Ferner E, Bonin S, Wöhnert J, Pütz J, Florentz C, Betat H, Sauter C, Mörl M.

Nucleic Acids Res. 2018 Sep 28;46(17):9170-9180. doi: 10.1093/nar/gky593. PMID: 29986062 

 

An intricate balance of hydrogen bonding, ion atmosphere and dynamics facilitates a seamless uracil to cytosine substitution in the U-turn of the neomycin-sensing riboswitch. 

Krepl M, Vögele J, Kruse H, Duchardt-Ferner E, Wöhnert J, Sponer J.

Nucleic Acids Res. 2018 Jul 27;46(13):6528-6543. doi: 10.1093/nar/gky490. PMID: 29893898 

2017

NMR experiments for the rapid identification of P=O···H-X type hydrogen bonds in nucleic acids. 

Duchardt-Ferner E, Wöhnert J.

J Biomol NMR. 2017 Oct;69(2):101-110. doi: 10.1007/s10858-017-0140-7. Epub 2017 Oct 14. PMID: 29032519 

 

Evaluation of 15N-detected H-N correlation experiments on increasingly large RNAs. 

Schnieders R, Richter C, Warhaut S, de Jesus V, Keyhani S, Duchardt-Ferner E, Keller H, Wöhnert J, Kuhn LT, Breeze AL, Bermel W, Schwalbe H, Fürtig B.

J Biomol NMR. 2017 Sep;69(1):31-44. doi: 10.1007/s10858-017-0132-7. Epub 2017 Sep 6. PMID: 28879611 

 

RNA structure refinement using NMR solvent accessibility data. 

Hartlmüller C, Günther JC, Wolter AC, Wöhnert J, Sattler M, Madl T.

Sci Rep. 2017 Jul 14;7(1):5393. doi: 10.1038/s41598-017-05821-z. PMID: 28710477 

 

Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation. 

Steinert H, Sochor F, Wacker A, Buck J, Helmling C, Hiller F, Keyhani S, Noeske J, Grimm S, Rudolph MM, Keller H, Mooney RA, Landick R, Suess B, Fürtig B, Wöhnert J, Schwalbe H.

Elife. 2017 May 25;6:e21297. doi: 10.7554/eLife.21297. PMID: 28541183 

 

NMR resonance assignments for the tetramethylrhodamine binding RNA aptamer 3 in complex with the ligand 5-carboxy-tetramethylrhodamine. 

Duchardt-Ferner E, Juen M, Kreutz C, Wöhnert J.

Biomol NMR Assign. 2017 Apr;11(1):29-34. doi: 10.1007/s12104-016-9715-6. Epub 2016 Oct 11. PMID: 27730489 

 

A Stably Protonated Adenine Nucleotide with a Highly Shifted pKa Value Stabilizes the Tertiary Structure of a GTP-Binding RNA Aptamer. 

Wolter AC, Weickhmann AK, Nasiri AH, Hantke K, Ohlenschläger O, Wunderlich CH, Kreutz C, Duchardt-Ferner E, Wöhnert J.

Angew Chem Int Ed Engl. 2017 Jan 2;56(1):401-404. doi: 10.1002/anie.201609184. Epub 2016 Nov 25. PMID: 27885761 

2016

An intermolecular G-quadruplex as the basis for GTP recognition in the class V-GTP aptamer. 

Nasiri AH, Wurm JP, Immer C, Weickhmann AK, Wöhnert J.

RNA. 2016 Nov;22(11):1750-1759. doi: 10.1261/rna.058909.116. Epub 2016 Sep 22. PMID: 27659052 

 

Characterization of the targeting signal in mitochondrial β-barrel proteins. 

Jores T, Klinger A, Groß LE, Kawano S, Flinner N, Duchardt-Ferner E, Wöhnert J, Kalbacher H, Endo T, Schleiff E, Rapaport D.

Nat Commun. 2016 Jun 27;7:12036. doi: 10.1038/ncomms12036. PMID: 27345737 

 

Ribosome biogenesis factor Tsr3 is the aminocarboxypropyl transferase responsible for 18S rRNA hypermodification in yeast and humans. 

Meyer B, Wurm JP, Sharma S, Immer C, Pogoryelov D, Kötter P, Lafontaine DL, Wöhnert J, Entian KD.

Nucleic Acids Res. 2016 May 19;44(9):4304-16. doi: 10.1093/nar/gkw244. Epub 2016 Apr 15. PMID: 27084949 

 

NMR resonance assignments for the class II GTP binding RNA aptamer in complex with GTP. 

Wolter AC, Duchardt-Ferner E, Nasiri AH, Hantke K, Wunderlich CH, Kreutz C, Wöhnert J.

Biomol NMR Assign. 2016 Apr;10(1):101-5. doi: 10.1007/s12104-015-9646-7. Epub 2015 Sep 15. PMID: 26373429 

 

What a Difference an OH Makes: Conformational Dynamics as the Basis for the Ligand Specificity of the Neomycin-Sensing Riboswitch. 

Duchardt-Ferner E, Gottstein-Schmidtke SR, Weigand JE, Ohlenschläger O, Wurm JP, Hammann C, Suess B, Wöhnert J.

Angew Chem Int Ed Engl. 2016 Jan 22;55(4):1527-30. doi: 10.1002/anie.201507365. Epub 2015 Dec 11. PMID: 26661511 

2015

The Solution Structure of the Lantibiotic Immunity Protein NisI and Its Interactions with Nisin. 

Hacker C, Christ NA, Duchardt-Ferner E, Korn S, Göbl C, Berninger L, Düsterhus S, Hellmich UA, Madl T, Kötter P, Entian KD, Wöhnert J.

J Biol Chem. 2015 Nov 27;290(48):28869-86. doi: 10.1074/jbc.M115.679969. Epub 2015 Oct 12. PMID: 26459561 

 

NMR resonance assignments of the lantibiotic immunity protein NisI from Lactococcus lactis. 

Hacker C, Christ NA, Duchardt-Ferner E, Korn S, Berninger L, Kötter P, Entian KD, Wöhnert J.

Biomol NMR Assign. 2015 Oct;9(2):293-7. doi: 10.1007/s12104-015-9595-1. Epub 2015 Jan 23. PMID: 25613223 

 

Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina. 

Chatterjee D, Kudlinzki D, Linhard V, Saxena K, Schieborr U, Gande SL, Wurm JP, Wöhnert J, Abele R, Rogov VV, Dötsch V, Osiewacz HD, Sreeramulu S, Schwalbe H.

J Biol Chem. 2015 Jun 26;290(26):16415-30. doi: 10.1074/jbc.M115.660829. Epub 2015 May 15. PMID: 25979334 

2014

Backbone and side chain NMR assignments for the ribosome assembly factor Nop6 from Saccharomyces cerevisiae. 

Wurm JP, Lioutikov A, Kötter P, Entian KD, Wöhnert J.

Biomol NMR Assign. 2014 Oct;8(2):345-8. doi: 10.1007/s12104-013-9514-2. Epub 2013 Aug 7. PMID: 23921755 

 

Building a stable RNA U-turn with a protonated cytidine. 

Gottstein-Schmidtke SR, Duchardt-Ferner E, Groher F, Weigand JE, Gottstein D, Suess B, Wöhnert J.

RNA. 2014 Aug;20(8):1163-72. doi: 10.1261/rna.043083.113. Epub 2014 Jun 20. PMID: 24951555 

 

Sequence elements distal to the ligand binding pocket modulate the efficiency of a synthetic riboswitch. 

Weigand JE, Gottstein-Schmidtke SR, Demolli S, Groher F, Duchardt-Ferner E, Wöhnert J, Suess B.

Chembiochem. 2014 Jul 21;15(11):1627-37. doi: 10.1002/cbic.201402067. Epub 2014 Jun 20. PMID: 24954073 

 

The importance of helix P1 stability for structural pre-organization and ligand binding affinity of the adenine riboswitch aptamer domain. 

Nozinovic S, Reining A, Kim YB, Noeske J, Schlepckow K, Wöhnert J, Schwalbe H.

RNA Biol. 2014;11(5):655-6. doi: 10.4161/rna.29439. Epub 2014 Jun 12. PMID: 24921630 

2013

Backbone resonance assignments for a homolog of the essential ribosome biogenesis factor Fap7 from P. horikoshii in its nucleotide-free and -bound forms. 

Hellmich UA, Wöhnert J.

Biomol NMR Assign. 2013 Oct;7(2):261-5. doi: 10.1007/s12104-012-9423-9. Epub 2012 Oct 5. PMID: 23054934 

 

Isotope labeling strategies for analysis of an ion channel cytoplasmic domain by NMR spectroscopy.

Abarca-Heidemann K, Duchardt-Ferner E, Wöhnert J, Rothberg BS.

Methods in Mol. Biol. 2013, 998:289-300

 

Essential ribosome assembly factor Fap7 regulates a hierarchy of RNA-protein interactions during small ribosomal subunit biogenesis. 

Hellmich UA, Weis BL, Lioutikov A, Wurm JP, Kaiser M, Christ NA, Hantke K, Kötter P, Entian KD, Schleiff E, Wöhnert J.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15253-8. doi: 10.1073/pnas.1306389110. Epub 2013 Sep 3. PMID: 24003121 

 

Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera. 

Steimer L, Wurm JP, Linden MH, Rudolph MG, Wöhnert J, Klostermeier D.

Nucleic Acids Res. 2013 Jul;41(12):6259-72. doi: 10.1093/nar/gkt323. Epub 2013 Apr 25. PMID: 23625962 

 

Essential requirements for the detection and degradation of invaders by the Haloferax volcanii CRISPR/Cas system I-B. 

Maier LK, Lange SJ, Stoll B, Haas KA, Fischer S, Fischer E, Duchardt-Ferner E, Wöhnert J, Backofen R, Marchfelder A.

RNA Biol. 2013 May;10(5):865-74. doi: 10.4161/rna.24282. Epub 2013 Apr 17. PMID: 23594992 

2012

Xentrivalpeptides A-Q: depsipeptide diversification in Xenorhabdus. 

Zhou Q, Dowling A, Heide H, Wöhnert J, Brandt U, Baum J, Ffrench-Constant R, Bode HB.

J Nat Prod. 2012 Oct 26;75(10):1717-22. doi: 10.1021/np300279g. Epub 2012 Oct 1. PMID: 23025386 

 

The First structure of a lantibiotic immunity protein, SpaI from Bacillus subtilis, reveals a novel fold. 

Christ NA, Bochmann S, Gottstein D, Duchardt-Ferner E, Hellmich UA, Düsterhus S, Kötter P, Güntert P, Entian KD, Wöhnert J.

J Biol Chem. 2012 Oct 12;287(42):35286-35298. doi: 10.1074/jbc.M112.401620. Epub 2012 Aug 17. PMID: 22904324 

 

Mechanisms for differentiation between cognate and near-cognate ligands by purine riboswitches. 

Wacker A, Buck J, Richter C, Schwalbe H, Wöhnert J.

RNA Biol. 2012 May;9(5):672-80. doi: 10.4161/rna.20106. Epub 2012 May 1. PMID: 22647526 

 

Structural and functional analysis of the archaeal endonuclease Nob1. 

Veith T, Martin R, Wurm JP, Weis BL, Duchardt-Ferner E, Safferthal C, Hennig R, Mirus O, Bohnsack MT, Wöhnert J, Schleiff E.

Nucleic Acids Res. 2012 Apr;40(7):3259-74. doi: 10.1093/nar/gkr1186. Epub 2011 Dec 10. PMID: 22156373 

 

Backbone NMR resonance assignments of the nucleotide binding domain of the ABC multidrug transporter LmrA from Lactococcus lactis in its ADP-bound state. 

Hellmich UA, Duchardt-Ferner E, Glaubitz C, Wöhnert J.

Biomol NMR Assign. 2012 Apr;6(1):69-73. doi: 10.1007/s12104-011-9327-0. Epub 2011 Jul 23. PMID: 21786024 

 

Backbone and side chain NMR resonance assignments for an archaeal homolog of the endonuclease Nob1 involved in ribosome biogenesis. 

Veith T, Wurm JP, Duchardt-Ferner E, Weis B, Martin R, Safferthal C, Bohnsack MT, Schleiff E, Wöhnert J.

Biomol NMR Assign. 2012 Apr;6(1):47-50. doi: 10.1007/s12104-011-9323-4. Epub 2011 Jul 6. PMID: 21732055 

 

NMR resonance assignment of the autoimmunity protein SpaI from Bacillus subtilis ATCC 6633. 

Christ NA, Duchardt-Ferner E, Düsterhus S, Kötter P, Entian KD, Wöhnert J.

Biomol NMR Assign. 2012 Apr;6(1):9-13. doi: 10.1007/s12104-011-9314-5. Epub 2011 Jun 5. PMID: 21643970 

 

Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs. 

Wurm JP, Griese M, Bahr U, Held M, Heckel A, Karas M, Soppa J, Wöhnert J.

RNA. 2012 Mar;18(3):412-20. doi: 10.1261/rna.028498.111. Epub 2012 Jan 24. PMID: 22274954 

2011

Influence of ground-state structure and Mg2+ binding on folding kinetics of the guanine-sensing riboswitch aptamer domain. 

Buck J, Wacker A, Warkentin E, Wöhnert J, Wirmer-Bartoschek J, Schwalbe H.

Nucleic Acids Res. 2011 Dec;39(22):9768-78. doi: 10.1093/nar/gkr664. Epub 2011 Sep 2. PMID: 21890900 

 

Rapid identification of noncanonical RNA structure elements by direct detection of OH···O=P, NH···O=P, and NH2···O=P hydrogen bonds in solution NMR spectroscopy. 

Duchardt-Ferner E, Ferner J, Wöhnert J.

Angew Chem Int Ed Engl. 2011 Aug 16;50(34):7927-30. doi: 10.1002/anie.201101743. Epub 2011 Jul 21. PMID: 21837618 

 

Structure and dynamics of the deoxyguanosine-sensing riboswitch studied by NMR-spectroscopy. 

Wacker A, Buck J, Mathieu D, Richter C, Wöhnert J, Schwalbe H.

Nucleic Acids Res. 2011 Aug;39(15):6802-12. doi: 10.1093/nar/gkr238. Epub 2011 May 16. PMID: 21576236 

 

Mechanistic insights into an engineered riboswitch: a switching element which confers riboswitch activity. 

Weigand JE, Schmidtke SR, Will TJ, Duchardt-Ferner E, Hammann C, Wöhnert J, Suess B.

Nucleic Acids Res. 2011 Apr;39(8):3363-72. doi: 10.1093/nar/gkq946. Epub 2010 Dec 11. PMID: 21149263 

 

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA. 

Meyer B, Wurm JP, Kötter P, Leisegang MS, Schilling V, Buchhaupt M, Held M, Bahr U, Karas M, Heckel A, Bohnsack MT, Wöhnert J, Entian KD.

Nucleic Acids Res. 2011 Mar;39(4):1526-37. doi: 10.1093/nar/gkq931. Epub 2010 Oct 23. PMID: 20972225 

2010

Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch. 

Duchardt-Ferner E, Weigand JE, Ohlenschläger O, Schmidtke SR, Suess B, Wöhnert J.

Angew Chem Int Ed Engl. 2010 Aug 16;49(35):6216-9. doi: 10.1002/anie.201001339. PMID: 20632338 

 

Dissecting the influence of Mg2+ on 3D architecture and ligand-binding of the guanine-sensing riboswitch aptamer domain. 

Buck J, Noeske J, Wöhnert J, Schwalbe H.

Nucleic Acids Res. 2010 Jul;38(12):4143-53. doi: 10.1093/nar/gkq138. Epub 2010 Mar 3. PMID: 20200045 

 

NMR resonance assignments of an engineered neomycin-sensing riboswitch RNA bound to ribostamycin and tobramycin. 

Schmidtke SR, Duchardt-Ferner E, Weigand JE, Suess B, Wöhnert J.

Biomol NMR Assign. 2010 Apr;4(1):115-8. doi: 10.1007/s12104-010-9223-z. Epub 2010 Mar 21. PMID: 20306311 

 

The ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase. 

Wurm JP, Meyer B, Bahr U, Held M, Frolow O, Kötter P, Engels JW, Heckel A, Karas M, Entian KD, Wöhnert J.

Nucleic Acids Res. 2010 Apr;38(7):2387-98. doi: 10.1093/nar/gkp1189. Epub 2010 Jan 4. PMID: 20047967

2009

Backbone resonance assignments of the 48 kDa dimeric putative 18S rRNA-methyltransferase Nep1 from Methanocaldococcus jannaschii.

Wurm JP, Duchardt E, Meyer B, Leal BZ, Kötter P, Entian KD, Wöhnert J.

Biomol NMR Assign. 2009 Dec;3(2):251-4. doi: 10.1007/s12104-009-9187-z. PMID: 19779849 

 

Molecular dynamics simulation study of the binding of purine bases to the aptamer domain of the guanine sensing riboswitch. 

Villa A, Wöhnert J, Stock G.

Nucleic Acids Res. 2009 Aug;37(14):4774-86. doi: 10.1093/nar/gkp486. Epub 2009 Jun 10. PMID: 19515936 

 

Structures of HIV TAR RNA-ligand complexes reveal higher binding stoichiometries. 

Ferner J, Suhartono M, Breitung S, Jonker HR, Hennig M, Wöhnert J, Göbel M, Schwalbe H.

Chembiochem. 2009 Jun 15;10(9):1490-4. doi: 10.1002/cbic.200900220. PMID: 19444830 

 

Time-resolved NMR spectroscopy: ligand-induced refolding of riboswitches. 

Buck J, Fürtig B, Noeske J, Wöhnert J, Schwalbe H.

Methods Mol Biol. 2009;540:161-71. doi: 10.1007/978-1-59745-558-9_12. PMID: 19381559

2008

Escherichia coli RNase P RNA: substrate ribose modifications at G+1, but not nucleotide -1/+73 base pairing, affect the transition state for cleavage chemistry. 

Cuzic S, Heidemann KA, Wöhnert J, Hartmann RK.

J Mol Biol. 2008 May 23;379(1):1-8. doi: 10.1016/j.jmb.2008.03.042. Epub 2008 Mar 28. PMID: 18452950 

 

NMR and MD studies of the temperature-dependent dynamics of RNA YNMG-tetraloops. 

Ferner J, Villa A, Duchardt E, Widjajakusuma E, Wöhnert J, Stock G, Schwalbe H.

Nucleic Acids Res. 2008 Apr;36(6):1928-40. doi: 10.1093/nar/gkm1183. Epub 2008 Feb 13. PMID: 18272534 

 

The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site. 

Taylor AB, Meyer B, Leal BZ, Kötter P, Schirf V, Demeler B, Hart PJ, Entian KD, Wöhnert J.

Nucleic Acids Res. 2008 Mar;36(5):1542-54. doi: 10.1093/nar/gkm1172. Epub 2008 Jan 21. PMID: 18208838

2007

Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution. 

Buck J, Fürtig B, Noeske J, Wöhnert J, Schwalbe H.

Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15699-704. doi: 10.1073/pnas.0703182104. Epub 2007 Sep 25. PMID: 17895388 

 

Double-lanthanide-binding tags: design, photophysical properties, and NMR applications. 

Martin LJ, Hähnke MJ, Nitz M, Wöhnert J, Silvaggi NR, Allen KN, Schwalbe H, Imperiali B.

J Am Chem Soc. 2007 Jun 6;129(22):7106-13. doi: 10.1021/ja070480v. Epub 2007 May 12. PMID: 17497862 

 

Metal-ion binding and metal-ion induced folding of the adenine-sensing riboswitch aptamer domain. 

Noeske J, Schwalbe H, Wöhnert J.

Nucleic Acids Res. 2007;35(15):5262-73. doi: 10.1093/nar/gkm565. Epub 2007 Aug 7. PMID: 17686787 

 

Structures of RNA switches: insight into molecular recognition and tertiary structure. 

Schwalbe H, Buck J, Fürtig B, Noeske J, Wöhnert J.

Angew Chem Int Ed Engl. 2007;46(8):1212-9. doi: 10.1002/anie.200604163. PMID: 17226886. Review.

 

Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch. 

Noeske J, Buck J, Fürtig B, Nasiri HR, Schwalbe H, Wöhnert J.

Nucleic Acids Res. 2007;35(2):572-83. doi: 10.1093/nar/gkl1094. Epub 2006 Dec 14. PMID: 17175531

 

L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy. 

Jonker HR, Ilin S, Grimm SK, Wöhnert J, Schwalbe H.

Nucleic Acids Res. 2007;35(2):441-54. doi: 10.1093/nar/gkl1066. Epub 2006 Dec 14. PMID: 17169991

2006

NMR in the SPINE Structural Proteomics project. 

Ab E, Atkinson AR, Banci L, Bertini I, Ciofi-Baffoni S, Brunner K, Diercks T, Dötsch V, Engelke F, Folkers GE, Griesinger C, Gronwald W, Günther U, Habeck M, de Jong RN, Kalbitzer HR, Kieffer B, Leeflang BR, Loss S, Luchinat C, Marquardsen T, Moskau D, Neidig KP, Nilges M, Piccioli M, Pierattelli R, Rieping W, Schippmann T, Schwalbe H, Travé G, Trenner J, Wöhnert J, Zweckstetter M, Kaptein R.

Acta Crystallogr D Biol Crystallogr. 2006 Oct;62(Pt 10):1150-61. doi: 10.1107/S0907444906032070. Epub 2006 Sep 19. PMID: 17001092 

 

Phosphate-group recognition by the aptamer domain of the thiamine pyrophosphate sensing riboswitch. 

Noeske J, Richter C, Stirnal E, Schwalbe H, Wöhnert J.

Chembiochem. 2006 Sep;7(9):1451-6. doi: 10.1002/cbic.200600151. PMID: 16871614 

2005

N-9,N-7-Dimethyl-hypoxanthiniumiodide.

Nasiri HR, Schwalbe H, Bolte M and Wöhnert J.

E - Structure reports online 2005, 61: O3353-O3354

 

Domain reorientation and induced fit upon RNA binding: solution structure and dynamics of ribosomal protein L11 from Thermotoga maritima. 

Ilin S, Hoskins A, Ohlenschläger O, Jonker HR, Schwalbe H, Wöhnert J.

Chembiochem. 2005 Sep;6(9):1611-8. doi: 10.1002/cbic.200500091. PMID: 16094695 

 

An intermolecular base triple as the basis of ligand specificity and affinity in the guanine- and adenine-sensing riboswitch RNAs. 

Noeske J, Richter C, Grundl MA, Nasiri HR, Schwalbe H, Wöhnert J.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1372-7. doi: 10.1073/pnas.0406347102. Epub 2005 Jan 21. PMID: 15665103

 

NMR assignments of the cold-shock protein ribosome-binding factor A (RbfA) from Thermotoga maritima. 

Grimm SK, Wöhnert J.

J Biomol NMR. 2005 Jan;31(1):73-4. doi: 10.1007/s10858-004-6065-y. PMID: 15692745

2004

Determination of the glycosidic bond angle chi in RNA from cross-correlated relaxation of CH dipolar coupling and N chemical shift anisotropy. 

Duchardt E, Richter C, Ohlenschläger O, Görlach M, Wöhnert J, Schwalbe H.

J Am Chem Soc. 2004 Feb 25;126(7):1962-70. doi: 10.1021/ja0367041. PMID: 14971929 

 

The structure of the stemloop D subdomain of coxsackievirus B3 cloverleaf RNA and its interaction with the proteinase 3C. 

Ohlenschläger O, Wöhnert J, Bucci E, Seitz S, Häfner S, Ramachandran R, Zell R, Görlach M.

Structure. 2004 Feb;12(2):237-48. doi: 10.1016/j.str.2004.01.014. PMID: 14962384

2003

Protein alignment by a coexpressed lanthanide-binding tag for the measurement of residual dipolar couplings. 

Wöhnert J, Franz KJ, Nitz M, Imperiali B, Schwalbe H.

J Am Chem Soc. 2003 Nov 5;125(44):13338-9. doi: 10.1021/ja036022d. PMID: 14583012 

 

NMR spectroscopy of RNA. 

Fürtig B, Richter C, Wöhnert J, Schwalbe H.

Chembiochem. 2003 Oct 6;4(10):936-62. doi: 10.1002/cbic.200300700. PMID: 14523911. Review.

 

Nuclear magnetic resonance studies of ribonucleic acids.

Ohlschläger O, Wöhnert J, Ramachandran R, Sich C and Görlach M.

Spectroscopy - Int. J. 2003, 17:537-547. Review.

 

Triple resonance experiments for the simultaneous correlation of H6/H5 and exchangeable protons of pyrimidine nucleotides in 13C,15N-labeled RNA applicable to larger RNA molecules. 

Wöhnert J, Görlach M, Schwalbe H.

J Biomol NMR. 2003 May;26(1):79-83. doi: 10.1023/a:1023040520291. PMID: 12766404 

 

NMR assignment of the full-length ribosomal protein L11 from Thermotoga maritima. 

Ilin S, Hoskins A, Schwalbe H, Wöhnert J.

J Biomol NMR. 2003 Feb;25(2):163-4. doi: 10.1023/a:1022256817250. PMID: 12652127 

1999

The NMR structure of the 5S rRNA E-domain-protein L25 complex shows preformed and induced recognition. 

Stoldt M, Wöhnert J, Ohlenschläger O, Görlach M, Brown LR.

EMBO J. 1999 Nov 15;18(22):6508-21. doi: 10.1093/emboj/18.22.6508. PMID: 10562563

 

Direct identification of NH...N hydrogen bonds in non-canonical base pairs of RNA by NMR spectroscopy. 

Wöhnert J, Dingley AJ, Stoldt M, Görlach M, Grzesiek S, Brown LR.

Nucleic Acids Res. 1999 Aug 1;27(15):3104-10. doi: 10.1093/nar/27.15.3104. PMID: 10454606 

 

Triple-resonance experiments for correlation of H5 and exchangeable pyrimidine base hydrogens in 13C,15N-labeled RNA. 

Wöhnert J, Ramachandran R, Görlach M, Brown LR.

J Magn Reson. 1999 Aug;139(2):430-3. doi: 10.1006/jmre.1999.1797. PMID: 10423381