Willkommen
Die zelluläre Homöostase und Überwachung beruhen auf dem Austausch von Informationen, Molekülen, und Organellen. Das Verständnis der molekularen Prinzipien st von grundlegender Bedeutung.
Abteilung Fragkostefanakis
Molecular Cell Biology of Plants
Information: Prof. Dr. Enrico Schleiff ist derzeit Präsident der Goethe-Universität Frankfurt.
The cellular homeostasis and surveillance depend on fluxes of information, molecules, proteins, RNAs and organelles. Understanding the molecular principles that ensure proper homeostasis and surveillance is fundamental for the description of the behaviour of an organism and its manipulation by genetic engineering, breeding or a chemical treatment. Our team aims to understand central aspects of these processes. We focus on the fundaments of regulating the life cycle of proteins and the signal transduction systems to maintain the homeostatic state under changing environmental conditions using plant systems as a model.
The cellular homeostasis and surveillance depend on fluxes of information, molecules, proteins, RNAs and organelles. Understanding the molecular principles that ensure proper homeostasis and surveillance is fundamental for the description of the behaviour of an organism and its manipulation by genetic engineering, breeding or a chemical treatment. Our team aims to understand central aspects of these processes. We focus on the fundaments of regulating the life cycle of proteins and the signal transduction systems to maintain the homeostatic state under changing environmental conditions using plant systems as a model.
On the one hand, plant cells operate as eukaryotic cells where fundamental principles are globally conserved. However, plant cells are more complex than animal cells due to the existence of the plastids. On the other hand, in conjunction with the increase of the global population, climate change requires intensive plant research to ensure the production of food and renewable energy resources.
Altogether, the unified research in these four fields will lead to a global understanding of the molecular principles that allow cellular homeostasis and surveillance.
The spectrum of our methods ranges from the investigation of the structure and function of single proteins over the analysis of energetic processes in isolated membranes, and evolutionary processes, to genetic analysis of environmentally regulated processes in plants using different plant model systems.
